An advanced version of a web-based instant response system, CloudClassRoom (CCR), which incorporates gaming features (competitive and mentally stimulating) entitled GEARS (Gamified Electronic Audience Response System), has been developed by Dr. Chun-Yen Chang’s research team. CCR-GEARS is written in HTML 5.0 and works on every Internet-capable device without software or plug-in installation. CCR enables teachers and students to participate in question-answering activities by using their own mobile devices, such as laptops, smartphones, or tablets. By this means, every student in the classroom can express their thoughts instantly as well as anonymously. CCR provides the teacher with a rough picture of student learning progress in real-time. Leveraging the capacity of mobile devices, CCR supports text and multimedia responses. We recently added a gaming feature (GEARS) to CCR, which, to the best of our knowledge, is the first instance in the world of incorporating gamification into an Instant Response System. GEARS encompasses the following functions: 1) learners will gain points when providing a correct answer; 2) learners may use the earned points to exchange ‘weapons/props’ to answer the following questions; 3) the weapons/props enable the features of ‘time extension’, ‘option deletion’, ‘the whole-class answer patterns’ and ‘peek into someone else’s answer’; 4) a completion board is renewed after each question, and finally 5) winners are able to ‘make’ their public statements. There will be more gaming functions added, and research conducted about this new adventure. Findings suggest that CCR can stimulate students’ learning motivation and improve their achievement in science.