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Record breaking Patent Transfer Fee at NTNU from the Dept. of Chemistry


It’s proven fact that free radicals attack cells, acerating aging and even cause cancer. Prof. Lee Way Zen from the Department of Chemistry spent ten years to developing artificial enzyme, superoxide dismutase, that helps break down potentially harmful oxygen molecules in cells. This is the first anti superoxide radical element that can be kept in room temperature. This key technology has received eight patent approvals in seven countries and the technology is transferred to Ti-UNic Biotech for producing cosmetics. 

Although superoxide radical is one of the key elements of body function, it must be kept at low concentration. A research has shown that more than 80% major diseases are related to radicals, including cardiovascular diseases, neurodegenerative diseases, cataracts, chronic inflammation of various organs, skin and body aging, and even cancer.

Prof. Lee Way Zen has been working on superoxide dismutase SOD since 2010. It is tested that in organic solvent, superoxide dismutase 96% superoxide radical in 4 minutes, preventing mitochondrion from being attached and reduce inflammation.


Since 2014, this key technology has successively obtained eight patents in seven countries including the Republic of China, the United States, Japan, Germany, Canada, the United Kingdom, and Malaysia. It effectively inhibits excessive superoxide free radicals in the human body. Research shown that it can effectively delay neurodegenerative diseases and relieve chronic inflammation of organs such as overactive bladder. In 2018, under the assistant of NTNU Research and Development Center, NTNU signed a contract with TI-UNIC Precision for patent transfer with nearly 10 million NTD, a record-breaking price at NTNU. A company that is willing to invest the patented technology of NTNU, to mass produce and distribute, reaching the best result of industry and academic collaboration.